Neuroimmunology and
Multiple Sclerosis Research

Our research program explores why the brain’s capacity for myelin repair declines with age. This loss of regenerative ability plays a significant role in the transition from relapsing remitting to progressive multiple sclerosis (MS). My lab is particularly interested in the contributions of telomere shortening, cellular senescence and changes in the extracellular matrix (ECM) to impaired remyelination during aging. Our goal is to identify therapeutic targets that can rejuvenate the aging central nervous system and restore its regenerative capacity, thereby enhancing remyelination and slowing MS progression.